Screening technology for detection of congenital heart diseases in neonates

• Anna L. Karpova
• Ekaterina L. Bokeriya
• T.N. Nikolaeva
• Evgeniy M. Spivak
• Aleksey V. Mostovoy
• A. V. Marasina

Abstract

Information about the methods for early detection of congenital heart diseases in neonates, which are used in the world practice as a screening technology, is presented in this review. The urgency and importance of screening for congenital heart disease in the early neonatal period as a way to reduce infant mortality were shown.

Special attention is given to the targeted clinical examination of the neonate and blood pressure measure­ment for early detection of different cardiac pathologic conditions. It emphasizes the need for supplement of clinical examination methods during the early neonatal period of the screening of blood oxygen saturation.

It emphasizes the need for supplement of clinical examination methods during the early neonatal period with the blood oxygen saturation screening. The most detailed information is provided about blood oxygen saturation screening in neonates, about the advantages and disadvantages of the method, its sensitivity and specificity, about the benefits of the more later pulse oximetry screning in neonates for detection of critical congenital heart diseases, and also information about analysis of the false positive and false negative results, and methods to reduce them.

Keywords:newborn infants, oxygen saturation, congenital heart diseases, blood pressure, peripheral vascular pulsation

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