References
1. Gale C., Statnikov Y., Jawad S., Uthaya S., Modi N.; on behalf of the Brain Injuries Expert Working Group. Neonatal brain injuries in England: population-based incidence derived from routinely recorded clinical data held in the National Neonatal Research Database. Arch Dis Child Fetal Neonatal Ed. 2018; 103: F301–6.
2. Lee A., Kozuki N., Blencowe H., Vos T., Bahalim A., Darmstadt G., et al. Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990. Pediatr Res. 2013; 74: 50–72.
3. Roychoudhury S., Esser M.J., Buchhalter J., Bello-Espinosa L., Zein H., Howlett A., et al. Implementation of neonatal neurocritical care program improved short-term outcomes in neonates with moderate-to-severe hypoxic ischemic encephalopathy. Pediatr Neurol. 2019: 101: 64–70.
4. Azzopardi D., Strohm B., Edwards A., Dyet L., Halliday H., Juszczak E., et al. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med. 2009; 361: 1349–58.
5. Armstrong K., Franklin O., Sweetman D., Molloy E. Cardiovascular dysfunction in infants with neonatal encephalopathy. Arch Dis Child. 2012; 97: 372–5.
6. Jary S., Lee-Kelland R., Tonks J., Cowan F., Thoresen M., Chakkarapani E. Motor performance and cognitive correlates in children cooled for neonatal encephalopathy without cerebral palsy at school age. Acta Paediatr. 2019; 108: 1773–80.
7. Lee-Kelland R., Jary S., Tonks J., Cowan F., Thoresen M., Chakkarapani E. School-age outcomes of children without cerebral palsy cooled for neonatal hypoxic-ischaemic encephalopathy in 2008-2010. Arch Dis Child Fetal Neonatal Ed. 2020; 105: 8-13.
8. Popescu M.R., Panaitescu A.M., Pavel B., Zagrean L., Peltecu G., Zagrean A.M. Getting an early start in understanding perinatal asphyxia impact on the cardiovascular system. Front Pediatr. 2020; 8: 68.
9. Lakshminrusimha S., Shankaran S., Laptook A., McDonald S., Keszler M., Van Meurs K., et al. Pulmonary hypertension associated with hypoxic-ischemic encephalopathy-antecedent characteristics and comorbidities. J Pediatr. 2018; 196: 45-51.e3.
10. Aggarwal S., Natarajan G. Biventricular function on early echocardiograms in neonatal hypoxic-ischaemic encephalopathy. Acta Paediatr. 2017; 106: 1085-90.
11. Mitra S., Bale G., Meek J., Tachtsidis I., Robertson N.J. Cerebral near infrared spectroscopy monitoring in term infants with hypoxic ischemic encephalopathy - a systematic review. Front Neurol. 2020; 11: 393.
12. Noori S., Wlodaver A., Gottipati V., McCoy M., Schultz D., Escobedo M. Transitional changes in cardiac and cerebral hemodynamics in term neonates at birth. J Pediatr. 2012; 160: 943-8.
13. Rhee C.J., da Costa C.S., Austin T., Brady K.M., Czosnyka M., Lee J.K. Neonatal cerebrovascular autoregulation. Pediatr Res. 2018; 84: 602-10.
14. Giesinger R.E., El Shahed A.I., Castaldo M.P., Breatnach C.R., Chau V., Whyte H.E., et al. Impaired right ventricular performance is associated with adverse outcome after hypoxic ischemic encephalopathy. Am J Respir Crit Care Med. 2019; 200: 1294-305.
15. Giesinger R.E., Bailey L.J., Deshpande P., McNamara PJ. Hypoxic-ischemic encephalopathy and therapeutic hypothermia: the hemodynamic perspective. J Pediatr. 2017; 180: 22-30.e2.
16. Volpe J.J., Inder T.E., Darras B.T., de Vries L.S., du Plessis A.J., Neil J.J., et al. Volpe’s Neurology of the Newborn. Elsevier, 2018.
17. Greisen G. Autoregulation of cerebral blood flow in newborn babies. Early Hum Dev. 2005; 81: 423-8.
18. Wintermark P., Moessinger A.C., Gudinchet F., Meuli R. Perfusion-weighted magnetic resonance imaging patterns of hypoxic-ischemic encephalopathy in term neonates. J Magn Reson Imag. 2008; 28: 1019-25.
19. Wintermark P., Hansen A., Gregas M.C., Soul J., Labrecque M., Robertson R.L., et al. Brain perfusion in asphyxiated newborns treated with therapeutic hypothermia. AJNR Am J Neuroradiol. 2011; 32: 2023-9.
20. Hyttel-Sorensen S., Pellicer A., Alderliesten T., Austin T., van Bel F., Benders M., et al. Cerebral near infrared spectroscopy oximetry in extremely preterm infants: phase II randomised clinical trial. BMJ. 2015; 350: g7635.
21. Massaro A.N., Govindan R.B., Vezina G., Chang T., Andesca-vage N.N., Wang Y., et al. Impaired cerebral autoregulation and brain injury in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. J Neurophysiol. 2015; 114: 818-24.
22. Howlett J.A., Northington F.J., Gilmore M.M., Tekes A., Huis-man T.A., Parkinson C., et al. Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy. Pediatr Res. 2013; 74: 525-35.
23. Burton V.J., Gerner G., Cristofalo E., Chung S.E., Jennings J.M., Parkinson C., et al. A pilot cohort study of cerebral autoregulation and 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy who received therapeutic hypothermia. BMC Neurol. 2015; 15: 209.
24. Lee J.K., Poretti A., Perin J., Huisman T., Parkinson C., Chavez-Valdez R., et al. Optimizing cerebral autoregulation may decrease neonatal regional hypoxic-ischemic brain injury. Dev Neurosci. 2017; 39: 248-56.
25. Abelian A., Mund T., Curran M.D., Savill S.A., Mitra N., Charan C., et al. Towards accurate exclusion of neonatal bacterial meningitis: a feasibility study of a novel 16S rDNA PCR assay. BMC Infect Dis. 2020; 20: 441.
26. Peng S., Boudes E., Tan X., Saint-Martin C., Shevell M., Winter-mark P. Does near-infrared spectroscopy identify asphyxiated newborns at risk of developing brain injury during hypothermia treatment? Am J Peri-natol. 2015; 32: 555-64.
27. Lemmers P.M., Zwanenburg R.J., Benders M.J., de Vries L.S., Groenendaal F., van Bel F., et al. Cerebral oxygenation and brain activity after perinatal asphyxia: does hypothermia change their prognostic value? Pediatr Res. 2013; 74: 180-5.
28. Mitra S., Kendall G.S., Bainbridge A., Sokolska M., Dinan M., Uria-Avellanal C., et al. Proton magnetic resonance spectroscopy lactate/N-acetylaspartate within 2 weeks of birth accurately predicts 2-year motor, cognitive and language outcomes in neonatal encephalopathy after therapeutic hypothermia. Arch Dis Child Fetal Neonatal Ed. 2019; 104: F424-32.
29. Shah P., Riphagen S., Beyene J., Perlman M. Multiorgan dysfunction in infants with post-asphyxial hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. 2004; 89: F152-5.
30. Jedeikin R., Primhak A., Shennan A.T., Swyer P.R., Rowe R.D. Serial electrocardiographic changes in healthy and stressed neonates. Arch Dis Child. 1983; 58: 605-11.
31. DiSessa T.G., Leitner M., Ti C.C., Gluck L., Coen R., Friedman W.F. The cardiovascular effects of dopamine in the severely asphyxiated neonate. J Pediatr. 1981; 99: 772-6.
32. Mohammad K. Hemodynamic instability associated with increased risk of death or brain injury in neonates with hypoxic ischemic encephalopathy. J Neonatal Perinat Med. 2016; 9: 357-62.
33. Al Balushi A., Barbosa Vargas S., Maluorni J., Sanon P.N., Ram-pakakis E., Saint-Martin C., et al. Hypotension and brain injury in asphyxiated newborns treated with hypothermia. Am J Perinatol. 2018; 35: 31-8.
34. Bashir R.A., Vayalthrikkovil S., Espinoza L., Irvine L., Scott J., Mohammad K. Prevalence and characteristics of intracranial hemorrhages in neonates with hypoxic ischemic encephalopathy. Am J Perinatol. 2018; 35: 676-81.
35. Liu L., Yenari M. Therapeutic hypothermia: neuroprotective mechanisms. Front Biosci. 2007; 12: 816-25.
36. Liu X., Tooley J., Loberg E.M., Suleiman M.S., Thoresen M. Immediate hypothermia reduces cardiac troponin I after hypoxic-ischemic encephalopathy in newborn pigs. Pediatr Res. 2011; 70: 352-6.
37. More K.S., Sakhuja P., Giesinger R.E., Ting J.Y., Keyzers M., Sheth J.N., et al. Cardiovascular associations with abnormal brain magnetic resonance imaging in neonates with hypoxic ischemic encephalopathy undergoing therapeutic hypothermia and rewarming. Am J Perinatol. 2018; 35 (10): 979-89.
38. Joynt C., Cheung P.Y. Cardiovascular supportive therapies for neonates with asphyxia - a literature review of pre-clinical and clinical studies. Front Pediatr. 2018; 6: 363.
39. Benumof J.L., Wahrenbrock E.A. Dependency of hypoxic pulmonary vasoconstriction on temperature. J Appl Physiol Respir Environ Exerc Physiol. 1977; 42: 56-8.
40. Jacobs S.E., Berg M., Hunt R., Tarnow-Mordi W.O., Inder T.E., Davis P.G. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev. 2013; 1: CD003311.
41. Gagnon M.H., Wintermark P. Effect of persistent pulmonary hypertension on brain oxygenation in asphyxiated term newborns treated with hypothermia. J Matern Fetal Neonatal Med. 2016; 29: 2049-55.
42. Jain A., McNamara PJ. Persistent pulmonary hypertension of the newborn: advances in diagnosis and treatment. Semin Fetal Neonatal Med. 2015; 20 (4): 262-71.
43. Hochwald O., Jabr M., Osiovich H., Miller S.P., McNamara PJ., Lavoie P.M. Preferential cephalic redistribution of left ventricular cardiac output during therapeutic hypothermia for perinatal hypoxic-ischemic encephalopathy. J Pediatr. 2014; 164: 999-1004.e1.
44. Kumagai T., Higuchi R., Higa A., Tsuno Y., Hiramatsu C., Sugimoto T., et al. Correlation between echocardiographic superior vena cava flow and short-term outcome in infants with asphyxia. Early Hum Dev. 2013; 89: 307-10.
45. Wu T.W., Tamrazi B., Soleymani S., Seri I., Noori S. Hemodynamic changes during rewarming phase of whole-body hypothermia therapy in neonates with hypoxic-ischemic encephalopathy. J Pediatr. 2018; 197: 68-74.
46. Shah S.K., Khan A.M., Cox C.S. Jr. Pulmonary hypertensive crisis requiring ECMO associated with re-warming from whole body hypothermia for hypoxic ischemic encephalopathy: clinical observations from a case series. Eur J Pediatr Surg. 2010; 20: 205-6.
47. Dempsey E., Rabe H. The use of cardiotonic drugs in neonates. Clin Perinatol. 2019; 46 (2): 273-90.
48. Gupta S., Singh Y. Hemodynamics in the asphyxiated neonate and effects of therapeutic hypothermia. 2018: 503-20.