Analysis of the course of retinopathy of prematurity in the Republic of Mordovia

• Luydmila V. Ledyaikina
• Veronika S. Vereshchagina
• Larisa A. Balykova
• Svetlana B. Radynova
• Svetlana V. Aksenova
• Tatiyna I. Razdolkina
• Nadezhda I. Mikhaylova

Abstract

Objective. To analyze the course of retinopathy of prematurity (RP) in children with extremely low body weight (ELBW) and very low body weight (VLBW) in Mordovia.

Material and methods. A retrospective analysis of 202 patients charts at with gestational age 20-32 weeks, born in 2014-2020, was carried out at the Mordovia Regional Clinical Hospital of Mordovia (Saransk). Children with retinopathy of prematurity (ROP) were divided into two groups: the main group, divided into two subgroups: the 1^st - premature babies with ELBW (n=39) and the 2^nd - children with VLBW (n=63). And the control group (premature babies without retinopathy), also divided into two subgroups: ELBW (n=25) and VLBW (n=75). The results were processed using the statistical program Statistica 10.0.

Results. Children with ELBW with retinopathy in 100% of cases were born at a term of less than 30 weeks. In children with VLBW such children - 76%. In the group of children with ELBW and VLBW with retinopathy, significant factors are chronic placental insufficiency (CRF) (F - 0.95 and 0.92) and a history of miscarriages (F - 0.91 and 0.93). Children with ELBW in both groups quite often received red blood cell transfusions 4 or more times. In both groups of children with ELBW (58.9 and 48%), the patent ductus arteriosus functioned. The duration of respiratory support in children with both ELBW and VLBW in most cases did not exceed 10 days.

Conclusion. Significantly more often children with VLBW in the main group received more than 4 blood transfusions - 33.3% (p<0.05). In children with ELBW, stage II RP was more often observed (59.2%), in children with VLBW - in stage I (66.7%). In children with ELBW in both groups (97.4 and 92%, respectively), prematurity anemia prevailed.

Keywords:prematurity, retinopathy, extremely low body weight, very low body weight

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