Nutritional support for infants with cholestasis


Cholestatic liver disease in newborns and young children is a common cause of malnutrition. Many diseases have a chronic progressive course with the formation of biliary cirrhosis, liver failure and require early liver transplantation. Nutritional status is an important prognostic predictor of morbidity and mortality in patients both at the stage of waiting and after transplantation, which determines the importance of timely correction of the main macro- and micronutrients deficiency. Available literature data and our experience indicate the need to use a high-calorie diet with a high content of medium chain triglycerides, polyunsaturated fatty acids, protein, fat-soluble vitamins and minerals in this category of children.

Keywords:cholestasis; cholestatic liver diseases; medium-chain triglyceride; malnutrition; nutrition support

Funding. Nutricia.

Conflict of interest. The authors declare no conflict of interest.

For citation: Degtyareva A.V., Puchkova A.A., Dokshukina A.A., Albegova M.B. Nutritional support for infants with cholestasis. Neonatologiya: novosti, mneniya, obuchenie [Neonatology: News, Opinions, Training]. 2022; 10 (2): 29–37. DOI: (in Russian)


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Degtyarev Dmitriy Nikolaevich
Doctor of Medical Sciences, Professor, Deputy Director for Scientific Research of the V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Head of the Chair of Neonatology at the Clinical Institute of Children's Health named after N.F. Filatov, I.M. Sechenov First Moscow State Medical University, Chairman of the Ethics Committee of the Russian Society of Neonatologists, Moscow, Russian Federation

ORCID iD 0000-0001-8975-2425
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