Clinical guidelines and real clinical practice in diagnosis and treatment of cytomegalovirus infection in pregnant patients and newborns

Abstract

Cytomegalovirus infection (CMVI) is the leading causes of intrauterine disease and can lead to severe problems in physical, psychoneurological and intellectual development in newborns and infants. The following article discusses the diagnostic and treatment approach to acute and secondary CMVI in pregnant women, newborns and infants using the real-life clinical examples. An analysis of approaches to solving these issues was presented in a number of Russian Clinical Recommendations. Indications for prescribing anti-cytomegalovirus immunoglobulin, high-dose valacyclovir, ganciclovir, valganciclovir in pregnant, new-born and young children are discussed.

Keywords:cytomegalovirus infection; pregnancy; newborns; cytomegalovirus immune globulin; valganciclovir; valacyclovir

Funding. The study had no sponsor support.

Conflict of interest. The author declares no conflict of interest.

For citation: Shakhgildyan V.I. Clinical guidelines and real clinical practice in diagnosis and treatment of cytomegalovirus infection in pregnant patients and newborns. Neonatologiya: novosti, mneniya, obuchenie [Neonatology: News, Opinions, Training]. 2023; 11 (1): 83–91. DOI: https://doi.org/10.33029/2308-2402-2023-11-1-83-91 (in Russian)

Received 14.02.2023. Accepted 06.03.2023.

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CHIEF EDITOR
CHIEF EDITOR
Degtyarev Dmitriy Nikolaevich
Doctor of Medical Sciences, Professor, Deputy Director for Scientific Research of the V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Head of the Chair of Neonatology at the Clinical Institute of Children's Health named after N.F. Filatov, I.M. Sechenov First Moscow State Medical University, Chairman of the Ethics Committee of the Russian Society of Neonatologists, Moscow, Russian Federation

ORCID iD 0000-0001-8975-2425

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