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4 . 2014

Dysfunction of the top departments of a gastrointestinal tract at newborn in aspect of interrelation with microaspiration of gastric contents

Abstract

Considering the frequent development of the combined bronchopulmonary and gastrointestinal pathology caused by a community of an embryological origin expedient studying of nature of influence of dysfunctions of a gastrointestinal tract on bronchopulmonary system is. In article the detailed characteristic of anatomicofunctional features of a gastrointestinal tract of newborn children is given, and also the most significant pathological factors promoting development of functional pathology of gastrointestinal system in the neonatal period are allocated. Pathogenetic mechanisms of development of microaspiration of gastric contents, and also morphological and histochemical changes in bronchopulmonary system under the influence of acid and peptic components in tracheobronchial aspirate are described.

Keywords:gastrointestinal tract, gastroesophageal reflux, bronchopulmonary system, microaspiration

Neonatology: News, Opinions, Training. 2014; (4): 48–54.

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Degtyarev Dmitriy Nikolaevich
Doctor of Medical Sciences, Professor, Deputy Director for Scientific Research of the V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Head of the Chair of Neonatology at the Clinical Institute of Children's Health named after N.F. Filatov, I.M. Sechenov First Moscow State Medical University, Chairman of the Ethics Committee of the Russian Society of Neonatologists, Moscow, Russian Federation

ORCID iD 0000-0001-8975-2425

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