Solution of chlorhexidine bigluconate and ethyl alcohol: what antiseptic is more effective for newborns?

• Oleg V. Ionov
• Irina V. Nikitina
• Anna R. Kirtbaya
• Ekaterina N. Balashova
• Anna A. Lenyushkina
• Lyudmila A. Lyubasovskaya
• Rodchenko Yu.V.
• Tatyana V. Priputnevich
• Victor V. Zubkov
• Dmitriy N. Degtyarev

Abstract

The aim - of this study was to evaluate the efficacy of 0.05% aqueous chlorhexidine bigluconate and 70% ethyl alcohol as antiseptic used for the treatment of the skin with сentral venous catheterization, in newborns undergoing treatment in the intensive care unit (NICU).

Material and methods during the prospective study examined 103 sample crops from the skin in 74 newborns were treated in NICU from January 2015 to June 2016 and required in the treatment of central venous catheterization.

The results of the 103 studied microbiological crops from the surface of the skin 74 of newborn children prior to catheterization of the central vein in 36 (35.0%) cases was obtained growth of conditionally pathogenic microorganisms. In 32 cases out of 36 antiseptic treatment of the skin prior to central venous catheterization was carried out with an aqueous solution chlorexidine bigluconate 0.05% in the remaining 4 cases - solution of ethyl alcohol 70%. It is established that 0.05% aqueous solution of chlorhexidine bigluconate is less effective antiseptic compared with the 70% solution of ethyl alcohol. The use of 0.05% aqueous solution of chlorhexidine bigluconate in the process of central venous catheterization may be one of the possible reasons for the development of CLABSI in children-patients of NICU.

Keywords:health care-associated infections, nosocomial infection, newborn, newborns undergoing treatment in the intensive care unit, antiseptic, microbial seeding

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