Hemorrhagic brain injury in premature infants: pathogenesis and ultrasound diagnostics

Abstract

Hemorrhagic brain damage is the leading cause of adverse neurological consequences. It develops significantly more often in premature infants than in full-term infants. Ultrasound examination of the brain is widely used as a method of neuroimaging in newborns for the detection of hemorrhages in the germinal matrix, intraventricular hemorrhages, periventricular hemorrhagic infarction, posthemorrhagic dilation of the ventricles, hemorrhage in the cerebellum and cystic forms of ischemic white matter damage. The ultrasound picture of the brain damage depends on the hemorrhage localization and volume. The timing of the US study plays a pivotal role in interpreting the scan data. The article presents data about the pathogenesis and ultrasound characteristics of hemorrhagic brain lesions in premature infants, and various classifications of intraventricular hemorrhages.

Keywords:hemorrhagic brain injury; ultrasound diagnostics; deeply premature newborns

Funding. The work was carried out within the framework of the state assignment: “Predictors and dynamics of neurological disorders in extremely premature infants with extremely low birth weight and very low birth weight”.

Conflict of interest. The authors declare no conflict of interest.

Contribution. All authors made equal contributions to the preparation of the article for publication.

For citation: Bykova Yu.K., Ushakova L. V., Filippova E. A., Sugak A. B., Kirtbaya A. R., Vatolin K. V., Suvorov I. A., Suvorova D.Yu. Hemorrhagic brain injury in premature infants: pathogenesis and ultrasound diagnostics. Neonatologiya: novosti, mneniya, obuchenie [Neonatology: News, Opinions, Training]. 2024; 12 (1): 47–57. DOI: https://doi.org/10.33029/2308-2402-2024-12-1-47-57 (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Degtyarev Dmitriy Nikolaevich
Doctor of Medical Sciences, Professor, Deputy Director for Scientific Research of the V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Head of the Chair of Neonatology at the Clinical Institute of Children's Health named after N.F. Filatov, I.M. Sechenov First Moscow State Medical University, Chairman of the Ethics Committee of the Russian Society of Neonatologists, Moscow, Russian Federation

ORCID iD 0000-0001-8975-2425

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