Respiratory, neurological and structure-functional sequellae of bronchopulmonary dysplasia in children and adults

• Boytsova E.V.
• Zapevalova E.Yu.
• Dmitry Yu. Ovsyannikov

Abstract

Data on respiratory, functional, structural and neurologic effects of bronchopulmonary dysplasia (BPD) in children, teenagers and young adults are presented in this review based on extensive literature and the results of our studies. Presented data argue in favor of external respiration failure persistence, including bronchial permeability failure, pulmonary diffusing capacity decreasing, hyperinflation and bronchial hyperactivity in these patients at a later age, and also remaining changes in pulmonary tissue structure. During the computer tomography of the lungs, persistent changes in the form of nonhomogenous ventilation / mosaic perfusion, raised lightness of a pulmonary tissue and emphysema in combination with local fibrous changes are defined. Designation of patients with bronchopulmonary dysplasia in anamnesis to the risk group of chronic obstructive pulmonary disease early development is proved. Bronchopulmonary dysplasia is an additional risk factor of adverse neurologic outcomes appearance, including infantile cerebral paralysis and arrested development.

Keywords:bronchopulmonary dysplasia, after-effects, respiratory function, X-ray, adults

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